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Description
Invivo Anti-Mouse Myeloperoxidase (MPO) Recombinant mAbProduct Specification Host Mouse Antigen Myeloperoxidase (MPO) Synonyms Mpo Location Lysosome Accession P11247 Clone Number S 3295 Antibody Type Recombinant mAb Application ELISA, WB, in vivo administration, in vitro administration Reactivity Ms Purification Protein G Concentration 5 mg ml Purity >95%(Determined by SDS PAGE) Endotoxin <1EU mg Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, pH 7. 4, Contains no stabilizers or
Product Specification
| Host | Mouse |
| Antigen | Myeloperoxidase (MPO) |
| Synonyms | Mpo |
| Location | Lysosome |
| Accession | P11247 |
| Clone Number | S-3295 |
| Antibody Type | Recombinant mAb |
| Application | ELISA, WB, in vivo administration, in vitro administration |
| Reactivity | Ms |
| Purification | Protein G |
| Concentration | 5 mg/ml |
| Purity | >95%(Determined by SDS-PAGE) |
| Endotoxin | <1EU/mg |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, pH 7.4, Contains no stabilizers or preservatives |
| Stability & Storage | 2 to 8 °C for 2 weeks under sterile conditions; |
Dilution
| application | dilution | species |
| WB | 1:500 | Ms |
| FCM | 5μl per million cells in 100μl volume |
Background
Myeloperoxidase (MPO) is a ~150 kDa heme-containing glycoprotein stored in the azurophilic granules of neutrophils and monocytes that, upon degranulation, generates potent hypohalous acids (especially hypochlorous acid from H2O2 and Cl⁻) and reactive radical species to kill engulfed pathogens, but when released extracellularly it can oxidatively damage host lipids, proteins and DNA, thereby linking innate immunity to chronic inflammatory, cardiovascular and neurodegenerative diseases.
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